A New Pharmacological Treatment for Intermittent Claudication:
نویسندگان
چکیده
منابع مشابه
A new pharmacological treatment for intermittent claudication: results of a randomized, multicenter trial.
BACKGROUND Effective medication is limited for the relief of intermittent claudication, a common manifestation of arterial occlusive disease. Cilostazol is a potent inhibitor of platelet aggregation with vasodilation effects. OBJECTIVE To evaluate the safety and efficacy of cilostazol for the treatment of intermittent claudication. METHODS Thirty-seven outpatient vascular medicine clinics a...
متن کاملPharmacological treatment of intermittent claudication does not have a significant effect on gait impairments during claudication pain.
Peripheral arterial disease (PAD) is a manifestation of atherosclerosis resulting in intermittent claudication (IC) or leg pain during physical activity. Two drugs (cilostazol and pentoxifylline) are approved for treatment of IC. Our previous work has reported no significant differences in gait biomechanics before and after drug interventions when PAD patients walked without pain. However, it i...
متن کاملinterspinous process implantation for the treatment of neurogenic intermittent claudication
results compared to pre-op scores, pf, ss, and vas scores for back, buttock and leg pain had a significant mean decrease at 6, 12, 24 months post-op (p < 0.05). based on the zcq and vas scores, a success rate of 79% (27.34), 78% (30.38) and 74% (17.23) were achieved at six months, 12 months, and 24 months respectively. conclusions x-stop is a safe and effective treatment for nic that provides m...
متن کاملPentoxifylline for intermittent claudication.
BACKGROUND Intermittent claudication (IC) is a symptom of peripheral arterial disease (PAD) and is associated with high morbidity and mortality. Pentoxifylline, one of many drugs used to treat IC, acts by decreasing blood viscosity, improving erythrocyte flexibility and promoting microcirculatory flow and tissue oxygen concentration. Many studies have evaluated the efficacy of pentoxifylline in...
متن کاملBuflomedil for intermittent claudication.
BACKGROUND Intermittent claudication (IC) is pain caused by chronic occlusive arterial disease, that develops in a limb during exercise and is relieved with rest. Buflomedil is a vasoactive agent used to treat peripheral vascular disease. However, its clinical efficacy for IC has not yet been critically examined. This is an update of a Cochrane review first published in 2000, and previously upd...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 1999
ISSN: 0003-9926
DOI: 10.1001/archinte.159.17.2041